Pyridoxine hydrochloride, more commonly known as vitamin B-6, is an essential nutrient your body uses to produce the neurochemicals serotonin and norepinephrine, and myelin, the protective covering that surrounds your nerves. As an adult, you should consume between 1.3 and 1.9 mg of pyridoxine hydrochloride each day to maintain a healthy body, according to the Office of Dietary Supplements. If you take a vitamin B-6 supplement, talk with your doctor about the potential side effects of pyridoxine hydrochloride.
Upset Stomach
Treatment with pyridoxine hydrochloride may irritate your stomach or digestive tract. Stomach-related side effects of this supplement may include abdominal pain, nausea or vomiting, MayoClinic.com reports. Stomach discomfort may also cause a temporary decrease in your appetite.
Skin Reactions
You may develop unusual skin reaction following treatment with pyridoxine hydrochloride. Small, red, pus-filled skin lesions, called acne, may develop across your skin. You may also notice that your skin is more sensitive to sunlight, a side effect referred to as photosensitivity. Consult your doctor if you develop severe skin reactions, such as excessive peeling or blistering.
Sensory Neuropathy
Prolonged treatment with pyridoxine hydrochloride, especially at high dosages, may cause sensory neuropathy, the Linus Pauling Institute at Oregon State University warns. This side effect may result in the development of painful, numb or tingling sensations in your hands or feet. Numbness or tingling may make it difficult for you to move the affected body region normally and may lead to difficulty walking or poor coordination. Seek prompt care from your medical provider if you develop sensory neuropathy side effects while taking this vitamin B-6 supplement.
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