Progestin is a synthetic form of the female hormone progesterone that was developed as a hormone replacement medication. Progesterone, produced in the ovaries, is involved with regulating the menstrual cycle as well as ovulation. The Progestin version is used as a treatment for many medical conditions such as endometriosis and to ameliorate symptoms associated with menopause and more serious diagnoses like breast, uterine and renal malignancies. Also, it can be prescribed for hormonal contraception and menstrual cycle regulation. Progestin medications are prescribed under brand names that include Provera, Megace, Loestrin and as an injection known as Depo-Provera.
Common Side Effects
According to Family Doctor.org, Progestin-only birth control pills have fewer side effects than birth control methods that contain estrogen, yet side effects may occur such as cramping or abdominal pain, dizziness, nausea and vomiting as well as diarrhea. Additionally, one may experience fatigue and headaches, breast tenderness and fluid retention, as well as a gain in weight. Anther common side effect is a sense of nervous anxiety.
Less Common Effects
On rare occasions, progestin has been documented to produce infrequent effects that do not automatically require medical care. Some of these uncommon responses, according to the Mayo Clinic, include hot flashes, acne and brown spots on skin due to being in the sun (these may be permanent). In addition, there have been complaints of decreased sexual drive, hair loss and insomnia.
Serious Effects
There is the potential for more serious repercussions of taking this medication, the presentation of which requires immediate medical attention. These signs include spotting and lighter or heavier uterine bleeding between menstrual periods, or a complete absence of periods. In some cases, this medication has been known to produce depression, a rash response or increased lactation. Also, changes in the amount uterine bleeding during regular monthly menstruation periods, especially an increase in blood loss, should be reported to a physician. In the case of long-term usage, the potential for loss of bone mass exists that may enhance the development of osteoporosis. Thus, calcium supplements are recommended for women who end up being on this medication for a substantial amount of time.
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