Premenstrual dysphoric disorder, or PMDD, is a constellation of serious symptoms associated with the menstrual cycle, according to Womenshealth.gov. It is far less common than premenstrual syndrome but far more debilitating. PMDD can be treated with antidepressants and other medical therapies. But some supplements and other lifestyle changes may help ease symptoms, though not all of these treatments are proven, according to Womenshealth.gov. Consult your doctor before taking any supplement for PMDD.
Calcium
Calcium may help reduce the physical symptoms and mood swings associated with PMDD, according to the American Congress of Obstetricians and Gynecologists, or ACOG. A daily dose of 1,200 mg appears effective. You might want to add 400 international units of vitamin D, because it increases the body's ability to use calcium. Both calcium and vitamin D are also good for your bones.
Magnesium
Taking a daily 400 mg magnesium supplement may help reduce water retention, which can help ease bloating, breast tenderness and mood symptoms, according to ACOG. But the evidence for magnesium's benefits is limited, and you should talk to your doctor before taking it. High doses of magnesium can cause diarrhea and drops in blood pressure.
Vitamin B6
A few studies suggest that a daily dose of 100 mg of vitamin B6 may help, but the evidence is not very strong, according to the University of Maryland Medical Center. High doses of this vitamin can cause neurological problems and loss of sensation. Consult your doctor before trying vitamin B6 for PMDD.
Other Supplements
There is very limited research evidence that indicates that 400 mg of vitamin E may help reduce symptoms, according to ACOG. There are a number of herbal remedies that are sold as PMS remedies, but most of these are either untested or ineffective, according to ACOG. These include black cohosh, chasteberry and evening primrose oil. Taking large doses of these supplements could cause serious side effects or interact in dangerous ways with other medication you may be taking. Talk to your doctor before trying any of these remedies.
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