The human body cannot make essential omega-3 fatty acids, they must come from food. Tuna, mackerel, some plants and nut oils contain omega-3s, which play an important role in brain function and normal growth and development. The University of Maryland Medical Center recommends using omega-3 supplementation to lower the risk of chronic heart disease, cancer and arthritis, as well improve brain performance, memory and cognition. However, as with any other supplement or medication, you can take too much or encounter dangerous side effects. Consult your physician before taking omega-3 fatty acids.
Contamination
Some fish meats are contaminated with mercury and environmental toxins. These can be transferred to the fish oil supplements when they are used, according to MedlinePlus. Fish oil supplements should be purchased from reputable sources that test their products. Unfortunately, omega-3 supplements are not evaluated or tested by the US Food and Drug Administration approval because they are not medications but supplements. Some manufacturers will claim that their product is made without contaminants, but there are no agencies that oversee these claims and evaluate the company testing procedures.
Conversion
Omega-3 fatty acids supply the body with alpha-linolenic acid that is converted to two other fatty acids -- EPA and DHA. People with diabetes or schizophrenia may not be able to convert supplemental omega-3 fatty acids, according to the University of Maryland Medical Center website. If you suffer from either of these conditions it is important for you to get enough EPA and DHA from foods in your diet. By getting the essential fatty acids from foods your body will not have to convert them and you will not be deficient in these substances.
Decreased Immune Function
Omega-3 supplements may increase fasting blood sugar levels in all individuals that can create problems if you suffer from diabetes, according to the University of Maryland Medical Center. If you feel you need fish oil supplements to increase omega-3 fatty acids, consult your physician who can help you closely monitor your blood sugar and correct the dosage of your insulin. High doses of omega-3 fatty acids in fish oil decreases your immune system's vitality, according to MedlinePlus, which has significant implications to HIV or AIDS patients, the elderly or people with a compromised immune system. Reducing the effectiveness of the immune system in these conditions can be potentially life-threatening.
Medication Interaction
Omega-3 fish oil supplements may interfere with blood-pressure medications, according to MayoClinic. Drugs used to lower blood pressure taken with the supplement can cause blood pressure to drop too low. Alternatively, medication for high blood pressure won't be as effective because the fish oil counteracts its benefits.



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