Nexium is a proton pump inhibitor often prescribed for people with gastroesophageal reflux disease (GERD). Like any medication, Nexium can have side effects. Because Nexium reduces the production of stomach acid, some of its side effects involve absorption of vitamins and potential vitamin deficiencies.
Folic Acid and Vitamin B12
Nexium can cause a deficiency of folic acid. If you are deficient in folic acid, that in turn can lead to a deficiency of vitamin B12. If you are taking Nexium, talk to your doctor about taking a B vitamin supplement or drinking cranberry juice to help increase vitamin B12 absorption.
Beta Carotene
Beta carotene is a precursor to vitamin A. Nexium may prevent beta-carotene from being absorbed properly. Talk with your doctor about taking a beta-carotene supplement or eating more foods that contain beta carotene. Ask about the merits of taking a supplement with beta carotene versus supplemental vitamin A; there are medical considerations which may favor one over the other.
Calcium
You need stomach acid to absorb calcium, so Nexium could cause a calcium deficiency. Your doctor may recommend calcium supplements or recommend adding more calcium-rich foods to your diet. If your doctor recommends a calcium supplement, be sure to ask her to specify which form of calcium she thinks would be best for you.
Iron
Nexium can also interfere with the absorption of iron. Make sure your diet includes foods rich in iron. Unless your blood tests show anemia, you probably will not need a special iron supplement.


