Seasonale birth control pills are continuous-use pills, or extended-cycle oral contraceptives. They contain a combination of low-dose estrogen and progestin and are marketed towards women who desire to have only one period every three months. Seasonale users take the "active" pills for 84 days and then take the placebo or "inactive" pill for seven days. During these seven inactive days, the woman will have her period.
Breakthrough Bleeding
Breakthrough bleeding is bleeding that occurs in between menstrual periods. The bleeding is usually light to medium spotting. Seasonale users are warned that breakthrough bleeding may take up to a year to decrease and is more likely to occur than with use of a standard oral contraceptive. This is the most common side effect.
Nausea and Vomiting
Nausea and vomiting are side effects common to all oral contraceptives. Nausea can be decreased by taking the pill with milk or food. If vomiting occurs, you should use another form of contraception as a "back-up".
Weight Change
While taking Seasonale, you may experience a gain or loss in weight. Bloating and diarrhea may also occur. If you have diarrhea while taking Seasonale, also use an additional form of contraception. Do not change your diet or take diet pills without first consulting your physician.
Acne
Acne may worsen or improve while you are taking oral contraceptives. The hormones in the pill lead to different side effects for different people. Contact your health care provider if the acne becomes severe.
Abdominal Cramping
Abdominal cramping may also occur while taking Seasonale, as with many other birth control pills. You may experience painful periods and constipation. Pain medications may interfere with the efficacy of Seasonale. If you begin taking pain medication, your doctor may need to adjust your dosage of Seasonale.
Vaginal Irritation
Vaginal irritation can occur while taking the pill. This irritation may include itching, burning, redness and swelling. You may also notice a whitish vaginal discharge.
Breast Tenderness
Soreness and tenderness of the breasts may occur when taking oral contraceptives. You may also notice a discharge or swelling.
Serious Side Effects
Contact your physician immediately if you experience dizziness or fainting, blurry vision, severe lethargy, extreme mood changes or heavy bleeding that persists beyond seven consecutive days. Oral contraceptives increase the risk of clotting, stroke and heart attack. Cigarette smoking further increases these risks, so smokers should not take Seasonale or any other oral contraceptives.
Other Side Effects
This list is not inclusive of all common or severe side effects possible when taking Seasonale. Consult the prescribing information included with your prescription for a complete list of side effects or ask your doctor or pharmacist.



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