Niacin treats high cholesterol. Niacin can both raise HDL or "good" cholesterol and lower LDL or "bad" cholesterol. There are several side effects associated with a daily dosage of niacin. Before taking niacin, consult with your doctor.
Flushing
According to the Mayo Clinic, niacin causes flushing. Flushing is redness and heat of your skin. This generally occurs with a niacin dose of 1,000 mg or more. Flushing is a relatively harmless side effect, most people just find it annoying. There are things that you can do to prevent or reduce flushing. The Mayo Clinic recommends taking an aspirin before you take niacin. However, you should always check with your doctor before adding any additional medications.
Hepatitis
Hepatitis, an inflammation of the liver, can be caused by niacin. In a study published in the "Mayo Clinic Proceedings," by Jeff Etchason and colleagues in 1991, the potential of a low-dose time release niacin treatment was analyzed. Five of the participants developed hepatitis. In four of those five patients, symptoms of hepatitis began just two days to seven weeks into therapy. Always tell your doctor if you have any history of liver disease, before starting any new medication.
Hyperglycemia
Hyperglycemia is a potential side effect of a regular dose of niacin. Niacin can effect glycemic control by reducing insulin sensitivity. According to a report in "Clinical Diabetes" by Dr. Maria P. Solano and Dr. Ronald B. Goldberg, published in 2006, niacin can worsen diabetic control. This report states that you should take extra care in monitoring blood glucose when on niacin. If you have a history of poor glycemic control, an adjustment of diabetes medications may be needed.
Other Side Effects
Some other common side effects reported with a daily dose of niacin can include intestinal and head related discomforts. According to the Mayo Clinic, reported side effects include upset stomach, headache and dizziness. If any of these side effects become intolerable, consult with your doctor.



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