Acomplia, also known as rimonabant and Zimulti, is a prescription drug used primarily for weight loss. According to Drugs.com, it is the first drug in a new class of weight loss pills known as Cannabinoid-1 Receptor Blockers, or CB1. Although Acomplia is used mainly for weight loss, it can be used for other purposes under the supervision of a physician.
History
According to the FDA, Sanofi-aventis, the manufacturer of Acomplia, first began trials for their drug in 1999, after they submitted an investigational new drug application to the FDA's Division of Metabolism and Endocrinology Products, or DMEP. In 2005, after six years of trials, the DMEP approved Acomplia as a once-daily drug to be used for weight loss and the prevention of weight gain in people with a body mass index greater than 30 and who exhibit risks of hypertension and diabetes. Acomplia was approved in Britain on June 28th, 2006 and was later approved by other countries in Europe shortly thereafter.
Uses
Acomplia is meant to be used in patients who are considered to be overweight, obese, and/or have type 2 diabetes, in addition to a healthy diet and moderate exercise.
How it works
Drugs.com claims that this weight loss pill works by blocking the CB1 receptors that are necessary for the metabolism of glucose and fat found in the liver, adipose tissue, and gastrointestinal tract. It also manages to turn off the brain receptors that cause cravings in people under the influence of marijuana.
Administration
International Anti-aging Systems suggests that Acomplia should always be consumed exactly as your doctor instructs. If you are unsure of how to take this pill, consult your doctor before using it. The average dose prescribed is 20mg to be taken in the morning on an empty stomach.
Warning
Like all drugs, Acomplia should be taken with the understanding that side effects may occur. These side effects include vomiting and nausea, which can be so severe that it caused 19 percent of patients to leave the study during the trial phase. You should not take this pill if If you have impaired liver, severely impaired renal function, are currently being treated for epilepsy, or if you are less than 18 years of age.
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