Prilosec is the brand name of omeprazole and is available as a capsule, tablet and granule. The tablets and capsules are available as delayed-release and immediate release, but the granules for suspension are delayed released. The delayed release tablet of 20 mg is available as an over-the-counter product; all other forms of the medication require a prescription. The OTC product is used for the treatment of heartburn that occurs for two days or more per week. Prescription Prilosec treats ulcers and signs and symptoms of gastroesophageal reflux disease, or GERD. It is also used for treating H. pylori infection.
Action
Prilosec belongs to the class of proton pump inhibitors, or PPIs. The drug blocks the actions of the cells found in the stomach and leads to suppression of acid release. This alleviates the symptoms of ulcers and GERD, particularly heartburn.
Administration
You should take Prilosec on an empty stomach, preferably before breakfast. Because the medication exerts its action in the stomach, food may delay the proper absorption and lead to inadequate treatment, according to the "Drug Information Handbook."
Triggers
Patients with ulcer or GERD should modify their diet to avoid stomach pain or worsening of symptoms. "Pharmacotherapy: A Pathophysiologic Approach" explains that there is no specific diet for these conditions, but certain foods and beverages, such as spicy foods, caffeine, acidic foods and alcohol should be avoided. You should also eat smaller meals to keep the stomach from getting too full; when your stomach is full, there is increased pressure and acid may flow up into the esophagus.
Foods to Eat
Many foods may help you to avoid heartburn and are recommended for regular use. PrilosecOTC.com suggests patients consume whole grains, such as brown rice, oatmeal, whole grain cereals, pasta, beans, peas, lentils and certain condiments, such as mustard and broth. Oils and vinegar should be used in moderation.
Side Effects on Stomach
The gastrointestinal side effects that may occur with Prilosec include nausea, stomach pain and diarrhea. The "Drug Information Handbook" reports that 2 percent to 5 percent of patients may experience these adverse effects. The side effects may affect the amount of food you eat or cause you to skip meals. However, do not skip meals because when you get hungry your body releases acid and this may worsen heartburn and stomach pain. These side effects should start to decrease as your body adjusts to the medication. If these side effects continue or worsen, contact your physician right away.
References
- "Drug Information Handbook"; Charles F. Lacy, Lora L. Armstrong, et al.; 2009
- "Pharmacotherapy: A Pathophysiologic Approach"; Joseph T. Dipiro, Robert L. Talbert, et al.; 2008
- PrilosecOTC.com: Heartburn Diet and Tips


