The U.S. Food and Drug Administration (FDA) announced on July 1, 2009, that it would require Pfizer, the makers of Chantix (varenicline), to include a warning of possible adverse psychological side effects on each prescription of Chantix. Because the psychological side effects of this drug are so varied, it is important that each patient be aware of the signs that may be detrimental to their mental health.
Behavior Patterns
Patients and their caregivers should watch for behavior patterns that might have a psychological source. According to the Mayo Clinic, changes in behavior such as aggression, irritability, hostility, agitation and panicking as well as reports of unusual sensations may be due to Chantix side effects. Dullness, drowsiness and sluggishness have also been reported, as well as problems sleeping, lack of sleep, unusual dreams and nightmares.
Thought Patterns
Reports of changes in thought patterns that have been attributed to Chantix use include depression or worsening of depression, suicidal thoughts and actions, and thoughts about death. In addition, according to the Chantix website, patients have experienced mood changes, manias, hallucinations, paranoia and confusion both during Chantix use and in the weeks following use.
Previous Mental Health
Patients who have already been diagnosed with depression and other mental health problems should talk to their doctor in depth about their mental state before beginning their use of Chantix. This will allow the patient, caregiver and physician to monitor possible psychological side effects more closely and determine whether Chantix is suitable for the individual.
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