Alli is an over-the-counter strength of the prescription drug orlistat. The 60 mg pills disable the enzyme lipase in the intestines. This stops the body from absorbing some of the fat eaten with meals. Because Alli alters the way the body absorbs food, there are some problems associated with taking Alli.
Treatment Effects
When taking Alli, no more than 15 g of fat can be consumed per meal. If more fat is consumed or if you are very sensitive to orlistat, treatment effects may occur. These include urgent diarrhea, oily flatulence, stomach cramping, fecal incontinence and stools that seem fatty or contain orange or brown oil. These effects can be minimized by sticking to a diet of 15 g or less per meal.
Liver Injury
Cases of liver injury by people taking Alli have been reported to the Food and Drug Administration, notes MayoClinic.com; however, no definite link between the two has been established. While taking Alli, you should still watch for signs of liver injury, such as a yellowing of your skin or the whites of your eyes. Dark or brown urine, fatigue and weakness are also signs of liver injury.
Allergic Reactions
As is the case with any medication, there is a risk of allergic reaction when taking Alli. If you notice your face, lips or tongue swelling, you may be having an allergic reaction. Itching, hives and trouble breathing are also signs of an allergic reaction.
Vitamin Deficiency
Because Alli blocks the absorption of some fat when you eat, you may need to take a vitamin supplement to ensure that you get proper nutrition. Vitamins A, D, E, and K are fat-soluble vitamins, which means that the absorption of these vitamins may be reduced while you are taking Alli.
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