Phenylephrine hydrochloride is a decongestant that's typically paired with other drugs so that it can treat a wider range of symptoms. Guaifenesin is the most common partner to phenylephrine HCL due to its ability to act as an expectorant. Phenylephrine is marketed as a substitute to psuedoephrine, which has become heavily regulated due to its use in the manufacture of illegal drugs. Phenylephrine is banned by the governing bodies of several sports.
Significance
If you suffer from congestion and want to exercise, phenylephrine may help alleviate symptoms such as nasal discomfort, sinus congestion and pressure. Phenylephrine acts as a vasoconstrictor or an agent that causes a shrinking of the blood vessels of the nasal cavity. Phenylephrine relieves symptoms of certain diseases but does not cure, treat or speed recovery time.
Types
Phenylephrine hydrochloride comes in several forms that can be taken to relieve symptoms. Intranasal sprays are used by placing the applicator into the nasal cavity, depressing the finger tabs to release the spray. Phenylephrine hydrochloride also comes in oral versions such as tablets, liquids and drops that are placed in the mouth and swallowed. In more severe cases, it can be administered by a subcutaneous injections.
Dosage
In the cases of intranasal application, Drugs.com says adults and children 12 and older are suggested to use one to two sprays or three drops in the nose every four hours. When using tablets orally, doctors suggest a dosage of 10mg to 15mg every four to six hours for adults and children 12 and older. Don't take more than 60mg a day.
Considerations
A study conducted by research teams from Hôpital Cochin in Paris, France, Carvalho, University Hospital in Coimbra, Portugal, and Laboratoire de Physiologie in Besançon, France showed that phenylephrine hydrochloride could be used for cases of mild asthma. In the study, 18 people were split into three groups according to severity of symptoms. Eleven people with moderate asthmatic symptoms felt a reduction in chest tightness after receiving subdermal injections of 100mg to 600mg. Researchers speculate that phenylephrine reduces smooth muscle contraction, which is a main feature of acute asthma, says the European Respiratory Journal.
Warning
When phenylephrine is incorrectly used, it can lead to hypertension, stroke, insomnia, tremors and seizures. It may also contribute to dysregulation of body temperature and heat illness. If you experience dizziness or palpitations while using phenylephrine and exercising, immediately discontinue your workout. Before taking medication prior to exercise, consult a medical professional.



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