Coenzyme Q-10, also called ubiquinone, is a substance found in every cell in the human body where it helps produce energy, the American Heart Association explains. This fat-soluble antioxidant is naturally found in certain types of food such as fish and whole grains. If you are unable to consume enough coenzyme Q-10 in your diet, your doctor may recommend treatment with a supplement. Talk with your doctor about the potential adverse effects of coenzyme Q-10 supplements before beginning treatment.
Upset Stomach
After taking a dose of coenzyme Q-10, you may develop stomach-related adverse effects. You may feel nauseous, begin vomiting or develop diarrhea, MedlinePlus warns. These stomach upset side effects may also cause a temporary decrease in your appetite. Eating a small snack before taking this type of supplement may help reduce or prevent stomach upset symptoms. If you experience chronic or recurrent bouts of diarrhea, contact your doctor. Diarrhea may increase your risk of becoming dehydrated due to excessive fluid loss from your body.
Skin Rash
A red, irritated skin rash may develop across your body as an adverse effect of this natural supplement. Your skin may also feel itchy or uncomfortable, MayoClinic.com reports. Excessive scratching of irritated patches of skin may elevate your risk of developing a skin infection.
Low Blood Pressure
Treatment with coenzyme Q-10 may cause an unusual drop in your blood pressure. Low blood pressure, or hypotension, may cause headache pain, dizziness or fatigue. If you already have low blood pressure levels, speak with your primary care physician before taking any type of supplement that contains coenzyme Q-10.



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