You may take HCG, or human chorionic gonadotropin, as an injection to help you overcome infertility if you are a woman, MayoClinic.com reports. HCG helps to stimulate the egg to develop properly within a woman's womb. B12, or cyanocobalamin, is a vitamin that helps you if you suffer from pernicious anemia or other problems caused by a deficiency of the B vitamin in your system, according to Drugs.com. It also is given either by muscle injection or into the layers of the skin. Both of these medications can produce side effects.
Diarrhea
Diarrhea may occur when you first take the B12 injection. Commonly, this can occur with virtually any new medication or supplement you take into your body as your system tries to acclimate to it. Diarrhea should occur in mild form, but may produce cramps in your abdomen. This side effect should go away within the first week. If it continues to occur or feels severe to you, contact your doctor for help.
Headaches and Dizziness
When first receiving the HCG injection you may experience a non-serious side effect of headaches, Drugs.com indicates. You also may experience headaches from B12 injections. The headaches should decrease as you get used to the medication. Dizziness also may occur from the B12 injections but that should stop as your body adjusts.
Depression
You may feel depressed at the start of the HCG hormonal injection treatment, Drugs.com indicates. Hormones change the way the brain receives messages within the central nervous system. You may want to rest more. As your body becomes increasingly used to the medication, you should feel more like yourself. If you continue to feel depressed, talk with your doctor for help.
Swelling and Tenderness
Your breasts may feel painful or tender when you first use HCG, but the sensation should end with further use. You also may experience swelling in your breasts, elsewhere in your body or at the site where the medication was injected. These classify as non-serious side effects and may occur at the onset of use of HCG, Drugs.com indicates. This is due to hormonal changes that occur taking this medication. It should stop after the first week or so. Swelling also may occur at the B12 injection site.
Irritability
When your body has a change in hormonal activity, you may feel a sense of irritability, Drugs.com indicates. As your body becomes accustomed to the medication, this should change. If it doesn't and you continue to feel irritable frequently, talk to your doctor, the organization recommends.
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