Calcium citrate is a dietary supplement for people who are lacking in calcium consumption. A rash from taking calcium citrate supplements is a sign of a severe allergic reaction, according to Drugs.com. Anaphylaxis is a rare, but life-threatening allergic reaction. If you develop hives or any other rash after taking calcium citrate, contact your doctor immediately. Calcium citrate is not recommended for people with a history of kidney stones or a parathyroid gland disorder. Talk with your doctor before taking calcium citrate.
Background
A skin rash from taking calcium citrate is a sign of anaphylaxis, because skin reactions are not a common side effect of taking the supplement. Hives are one of the first signs of anaphylaxis. Chemicals that typically don't cause harm flood your body and cause it to enter a state of shock. Your airways become constricted, making it difficult to breathe, and your blood pressure suddenly drops, making you feel lightheaded and dizzy, according to MayoClinc.com. The most common triggers of this type of allergic reaction are drugs, insect bites and certain food allergies.
Cause
After ingesting calcium citrate, the immune system mistakes the substance as dangerous to the body. A defense is built to attack to the supplement by creating specific antibodies, called IgE antibodies. These antibodies target the supplement and attempt to ward it off. The introduction of IgE antibodies into the blood alters mast cells that respond by producing histamine, according to MedlinePlus. Histamine is a hormone that helps stop infection and disease, but in extreme amounts it can be harmful.
Symptoms
The extreme levels of histamine throughout the body cause a disruption in vital bodily functions. Drugs.com states that common severe allergic reactions to calcium citrate include swelling in the face, lips, tongue or throat; hives; the inability to breathe normally; fainting; a weak but fast pulse; anxiety; and severe chest pain.
Treatment
A severe allergic reaction to calcium citrate will require emergency medical attention. The most effective medical treatment for anaphylactic shock is an injection of epinephrine. When this drug is administered intravenously, it restores normal blood pressure, opens the lungs and allows the heart to resume a normal rate.
Considerations
If you develop a rash reaction after taking calcium citrate without the symptoms of anaphylactic shock, discontinue use and call your doctor. You can treat the skin rash with hydrocortisone to reduce inflammation and itching.
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