Niacin is a vitamin B3 supplement that may help lower your "bad" or LDL cholesterol levels and increase your "good" or HDL cholesterol levels. This type of supplement may also be recommended if you have unusually low levels of niacin in your blood -- a condition called pellagra. The side effects of time-release niacin may be less severe than those induced by regular niacin supplements. Talk with your doctor about the side effects you may experience before beginning to take time-release niacin supplements.
Flushing
Time-release niacin is often recommended by medical professionals to help reduce your risk of developing flushing side effects, according to the University of Maryland Medical Center; however, flushing may still occur if you take this type of vitamin B-3 supplement. Symptoms associated with flushing include skin redness, itching, burning or tingling. You may also notice that your skin feels warm to the touch. These side effects typically subside within a few hours of taking niacin, but may recur following subsequent dosing.
Loose Stools
Treatment with time-release niacin may irritate your intestinal tract, resulting in diarrhea, PubMed Health warns. Diarrhea, or frequent, loose bowel movements, may be uncomfortable and can be accompanied by stomach bloating and cramping. Chronic diarrhea should be discussed with your doctor as this side effect may increase your risk of becoming dehydrated.
Stomach Upset
Stomach irritation caused by this type of niacin supplement may cause upset stomach side effects including nausea, vomiting or heartburn. If you feel sick to your stomach, you may also be uninterested in eating during your usual mealtimes. Seek care from your physician if stomach discomfort persists.
Liver Damage
Prolonged treatment with time-release niacin may increase your risk of developing liver damage, the UMMC warns. Symptoms associated with liver damage include abdominal pain, fatigue, itchy skin, upset stomach swelling or unusual yellowing of your skin. If you exhibit symptoms of liver damage, consult your primary medical provider as soon as possible to ensure you receive prompt and appropriate care.
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