Lycopene is the chemical compound found in tomatoes, watermelon and pink grapefruit that gives them their vibrant colors. In the human body, it can be found in the liver, skin, blood serum, adrenal glands, prostate gland and the colon. Lycopene has strong antioxidant properties and numerous studies indicate that it can help prevent certain cancers, macular degeneration and heart disease, according to MayoClinic.com. Lycopene is not a necessary nutrient, so no optimum dosage has been established. It can be obtained through the diet and is sold as nutritional supplements containing 10 to 40 mg. Some side effects have been noted with its use.
Allergic Reaction
It is possible to suffer an allergic reaction to Lycopene 40. Those with allergies to tomatoes and other lycopene-containing foods should not take this supplement. The signs of an allergic reaction to lycopene include an itchy skin rash with hives, difficulty breathing, wheezing, difficulty swallowing, dizziness and swelling of the face and throat. Individuals who experience any signs of an allergic reaction should consult a health care professional immediately.
Diarrhea
Because Lycopene 40 is a nutritional supplement, the FDA has not fully evaluated its safety. However, according to Baptist Health Systems, it is well-tolerated in the recommended dosage of no more than 75 mg per day, although occasional incidences of diarrhea, abdominal cramping, gas and bloating associated with its use have been reported.
Stomach Irritation
Lycopene 40 may cause stomach problems. These problems can include stomach upset, heartburn, nausea and vomiting. It is also possible for this supplement to irritate existing stomach ulcers due to the acidic nature of lycopene, according to MayoClinic.com. Taking the supplement with food may help reduce the occurrence of some of these side effects.
Skin Discoloration
Taking Lycopene 40 for an extended period of time can cause skin discoloration in some individuals. Supplements containing larger doses of lycopene can cause the skin to take on an orange hue, according to the American Cancer Society. This is due to the large amount of carotenoid chemicals contained in lycopene, which are responsible for the color of lycopene-containing foods. This skin discoloration is temporary and goes away when treatment with this supplement is discontinued.
May Interfere with Cancer Treatments
Although no human studies have been performed, the American Cancer Society warns that nutritional supplements containing antioxidants, such as Lycopene 40, may interfere with radiation therapy and chemotherapy if taken while undergoing these treatments. They advise relying on natural food sources of lycopene, such as tomatoes, during any treatment for cancer.
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