Human chorionic gonadotropin, or HCG, is a hormone produced during pregnancy that is used to treat infertility problems in women. It also is used to increase sperm counts in men and to treat pre-pubertal cryptorchidism in boys -- a condition when one or both testicles do not descend. This hormone is being marketed as a rapid weight-loss product; however, it is not approved or endorsed by the U.S. Food and Drug Administration to treat obesity. Talk to your doctor about possible interactions of this prescription drug, as side effects may occur from receiving HCG injections.
Injection Site Irritation
Right after receiving the HCG injection, you may develop localized side effects where the hormone was injected. For example, the injection site may be irritated and warm to touch, or painful and swollen, according to the Drugs.com. These reactions are temporary and usually subside within a day or two. If the site continues to be painful, swollen and red after several days, notify your physician so your symptoms can be evaluated.
Pain and Tenderness
As you receive HCG injections to lose weight, you may experience various types of pain in your body. For example, you may get headaches. Also, you may experience heightened pain sensitivity in the form of tenderness in your breasts. These side effects are considered mild and temporary, and they should subside once your body becomes adjusted to the HCG treatments. However, talk to your doctor if these side effects persist or increase in severity.
Fluid Retention
Another common side effect is edema, that is, the accumulation or retention of fluid, RxList.com reports. Edema usually occurs in the extremities, such as puffy or swollen feet or ankles, and occasionally in the abdomen, known as ascites. This side effect can become dangerous, especially if you have a medical history of certain conditions, such as heart disease or hypertension.
Mood Changes
When you first start taking HCG, it may cause you to have mood swings and feel depressed; for example, you could feel down. Also, you could become restless or irritable, according to Dietsinreview.com. These side effects tend to be temporary and subside, but if they continue or get worse, discuss this with your physician.



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