Hypothalamus Treatment For Weight Loss

The hypothalamus, a gland in the brain, controls the endocrine system, which releases hormones that provide signals to the body to regulate hunger and metabolism. Research into how those signals control weight and, when interrupted, may cause obesity is ongoing as of 2010. Treatments for the symptoms of hypothalamic dysfunction primarily focus on replacing hormones rather than treating the gland itself. A popular diet also claims to "re-set" the hypothalamus, but it is controversial.

Basics

The endocrine system secretes hormones, such as insulin and leptin, that influence many bodily functions, including metabolism and digestion. The hypothalamus is the main link between the nervous and endocrine systems as it regulates the pituitary gland, which in turn regulates the endocrine system. When the hypothalamus is not functioning properly, various symptoms may develop, depending on the hormones that are not properly cued. Based on these imbalances, overeating and obesity may result.

Causes

Disorders caused by hypothalamic dysfunction that can lead to weight gain include hypothyroidism and low adrenal function, which are generally caused by hormone insufficiency. These disorders can be diagnosed by testing your urine to determine your hormonal output. Tumors can also disrupt hypothalamic function and are detected through imaging tests such as MRIs. A condition called hypothalamic obesity can arise when the gland is damaged from events such as a tumor or treatments to remove one.

Treatments

Hormonal problems caused by hypothalamic dysfunction, such as hypothyroidism, are treated by replacing the missing hormones. These do not treat the hypothalamus itself but rather the symptoms caused by the dysfunction. Hypothalamic obesity has also been treated with hormones, according to the Pituitary Network Association. In addition, the condition has been resolved in very small studies with the administration of caffeine and ephedrine, and with gastric bypass surgery. Again, the hypothalamus itself was not treated.

Diet

A popular but controversial diet utilizes a human pregnancy hormone, HCG, in combination with a very low calorie diet to "re-set" the hypothalamus. Developed by a German physician in the 1950s, the HCG diet helps the body shed its "abnormal" fat stores rapidly. However, many doctors and nutritionists are concerned that the diet does not deliver enough nutrients or energy and that taking the pregnancy hormone may lead to tumor growth, reports the Seattle Times.

Considerations

Ongoing research into the roles of leptin, insulin and other hormones in the development of obesity is ongoing, along with research into the function of the hypothalamus and, in particular, the treatment of hypothalamic obesity. Before going on any diet, it is important to consult with your physician. Because it is a very low-caloric diet, the HCG diet should be followed only under your doctor's supervision.