Side Effects of Vegetarian Glucosamine

An estimated 2 percent of people in the United States suffer from an allergy to shellfish, according to the most recent statistics published in the July 2004 issues of the "Journal of Allergy and Clinical Immunology." People who are allergic to shellfish and also experience chronic osteoarthritis symptoms should not take traditional forms of glucosamine, as this supplement may contain shellfish and can induce a severe, life-threatening allergic reaction. An alternate form of glucosamine, called vegetarian or vegan glucosamine, is derived from corn rather than shellfish and can serve as a safe alternative for people with shellfish intolerance and persistent joint pain. Talk with your medical provider about the potential side effects of vegetarian or vegan glucosamine before you begin using this supplement.

Stomach Irritation

You may experience stomach irritation as a side effect of vegetarian glucosamine. This supplement may cause nausea, bloating, vomiting, heartburn or gas. These side effects may contribute to a temporary decrease in your usual appetite. Avoid taking vegetarian glucosamine on an empty stomach -- especially if you have a stomach or peptic ulcer -- to help limit or prevent stomach-related side effects, the University of Maryland Medical Center advises.

Insomnia or Drowsiness

Difficulty falling asleep or staying asleep through the night may occur while you are taking this supplement. Recurrent episodes of insomnia may cause daytime drowsiness. Increased fatigue during the day may affect limit your ability to concentrate or complete your daily tasks. If insomnia or drowsiness persists, consult your physician for further evaluation and care.

Bowel Movement Changes

Intestinal irritation caused by glucosamine supplements may lead to bowel movement changes. You may experience urgent, watery bowel movements accompanied by abdominal discomfort, fullness or cramping. Alternatively, treatment with this supplement may cause infrequent or difficult bowel movement that yield small, hard stools. Seek additional care from your medical provider if bowel movement changes persist. Chronic constipation or diarrhea may cause additional medication complications, such as bowel impaction or dehydration.

Skin Reactions

Mild skin reactions may develop as a side effect following treatment with vegetarian glucosamine. You may notice the appearance of small, irritated, red patches of skin across your body. Your skin may also be more sensitive to sunlight, which may increase your risk of developing a sun burn upon exposure to sunlight, MayoClinic.com reports. Any type of severe skin reaction, such as hives, peeling or blistering, should be reported to your doctor immediately.

Headache

While taking vegetarian glucosamine, you may experience recurrent headaches. Headache pain may disrupt your ability to remain focused, active or attentive during your daily activities. If headache pain is bothersome, consider taking an over-the-counter pain reliever to alleviate discomfort.

References

Article reviewed by Libby Swope Wiersema Last updated on: Apr 26, 2011

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