Parkinson's disease is a chronic neurological condition which causes coordination and movement difficulties, tremor, muscle stiffness and speech problems. It occurs when cells that produce dopamine, the chemical responsible for coordination and movement control, become damaged. Although there is no cure for Parkinson's disease, there are a number of medicines that can help to improve symptoms. Some vitamins may also help to support Parkinson's disease treatment and improve symptoms. However, scientific evidence to prove they can treat the disease itself is limited. Talk to your doctor before taking vitamin supplements as they may interfere with medicines you may be taking.
Examples
The University of Maryland Medical Center notes that vitamin B6 and vitamin C may benefit patients with Parkinson's disease. Vitamin B6 may reduce treatment-related side effects, while vitamin C, a potent antioxidant, may help to delay the need for Parkinson's medicines.
Efficacy
The results of a study published in the September 2010 issue of the "British Journal of Nutrition" show that a low intake of vitamin B-6 is associated with an increased risk of Parkinson's disease suggesting a role for this vitamin in the prevention of Parkinson's disease. Studies establishing a role for vitamin C in the treatment of Parkinson's disease are limited, however, an article published in the March 2009 issue of the medical journal "Free Radical Biology & Medicine" suggests that vitamin C may reduce oxidative stress in the brain and may modulate dopaminergic effects.
Sources
Vitamin B6, also known as pyridoxine, is a water-soluble vitamin found in a variety of foods including chicken, turkey, bread, oatmeal, eggs, vegetables, milk and potatoes. Vitamin C, also known as ascorbic acid, is present in foods including red peppers, citrus fruits, tomatoes and broccoli. Both vitamins can also be taken as a dietary supplement.
Use
UMMC recommends taking 1 g of vitamin C three times daily. However, this dose is intended to be a guideline only. The dose of vitamin B6 needed may vary according to whether you take this vitamin alone or as part of a B vitamin supplement. Talk to your doctor about the most appropriate dose of each vitamin for you.
Safety
Although vitamins are natural substances, taking excessive amounts in supplemental form may be harmful to your health. The U.K. Food Standards Agency notes that taking large amounts of vitamin B6 can cause long-term and often irreversible damage. For example, it may to peripheral neuropathy, a condition characterized by loss of feeling in the arms and legs. Vitamin C may cause side effects including diarrhea and nausea. It may also contribute to the development of kidney stones. Ensure you speak to a doctor before taking either of these vitamins to treat Parkinson's disease.
References
- NHS Choices: Parkinson's Disease
- University of Maryland Medical Center: Parkinson's Disease
- PubMed: Dietary Intake of Folate, Vitamin B6, Vitamin B12 and Riboflavin and Risk of Parkinson's Disease: A Case-Control study in Japan
- PubMed: Vitamin C Function in the Brain: Vital Role of the Ascorbate Transporter SVCT2.
- Food Standards Agency: Vitamin B6
- Office of Dietary Supplements: Vitamin C



Member Comments