Alli Compared to Xenical

Alli and Xenical are weight-loss medications that contain the active ingredient orlistat. These drugs are lipase inhibitors that block the amount of fat absorbed by the body. Instead of being stored in the body, the excess fat is excreted in bowel movements. Both of these drugs should only be taken by people who are overweight or obese. Xenical is approved for use by people who have a body mass index of 30 or more who are otherwise healthy or those with a BMI of 27 or more who have obesity-related health problems.

Dosage

The main difference between Alli and Xenical is that Alli is available over the counter and Xenical is available by prescription only. Alli is 60mg, while Xenical is 120mg. While Alli is approved for adults 18 years or older, Xenical is also available for children 12 to 18 years old with a doctor's approval. By taking these drugs as directed, you can lose up to 50 percent more weight than you would by following a healthy diet and exercise program. According to MayoClinic.com, Xenical nets an average weight loss of 5 to 7 lbs. in a year, while Alli nets an average weight loss of 3 to 5 lbs. per year. This is in addition to the 8 lbs. the average person will lose through diet and exercise alone.

Time Frame

Both Xenical and Alli are approved for long-term use, up to 12 months. MyAlli.com reports that the majority of weight loss attributed to Alli use is experienced during the first six months on the medication. You take each medication in three daily doses of one pill per dose, which you take with a meal or within an hour after eating a meal.

Plan Components

Alli and Xenical are meant to be used in conjunction with a low-fat diet and daily exercise program. Each meal should contain no more than 15g of fat. Eating more fat than recommended can cause unpleasant side effects, such as oily flatulence or uncontrollable diarrhea. If you are concerned about possible side effects, talk to your doctor about adjusting the dosage of these medications; however, it is unlikely that a lowered dosage will help treatment effects if you continue to eat meals that are high in fat. You should exercise at a moderate intensity for at least 30 minutes per day while taking either of these drugs. Swimming and walking are good exercise choices. While you exercise, you should sweat and your heart rate should increase, but you should still be able to talk. If you are taking Xenical, your doctor may have you meet with a dietitian and/or exercise physiologist to ensure you are eating and exercising properly.

Warnings

Because Xenical and Alli block the absorption of fat, taking supplements of fat soluble vitamins, including vitamins A, D, E and K, may be necessary. You should take these supplements at least two hours following your last dose of Alli or Xenical of the day so your body has time to absorb them properly. If your doctor prescribes Xenical, he will likely prescribe you some vitamins to take or he may recommend an over-the-counter vitamin.

Considerations

Because Alli is an over-the-counter medication, it is unlikely your insurance plan will cover the cost of Alli. However, some insurance plans may cover all or part of the cost of Xencial. If you are unsure of whether or not your insurance will cover these medications, contact your insurance provider or ask your pharmacist.