Aspartame is an artificial sweetener that has been implicated in causing health problems since its use in processed foods and medications. It is made from two naturally occuring amino acids, L-phenylalanine and L-aspartic acid; when combined, it provides a sweetness that is 200 times greater than regular sugar, as stated by Aspartame Information Center. Testing was performed on the sweetener and the Food and Drug Administration provided the sweetener with the title of GRAS, generally recognized as safe.
Agression
The Aspartame Information Center states to date, no studies have shown conclusive evidence that aspartame causes aggressive behavior in children. Dr. Paul, a pediatrician, states that in small amounts found in medication, aspartame is safe for children. Drinking diet drinks is not considered safe as the amount of aspartame consumed by a small child is twice the recommended amount.
Brain Tumors
Aspartame has been stated to cause brain tumors in monkeys used to test the safety of the artificial sweetener. Osteopathic physician Dr. Mercola states that long-term use of phenylalanine products increases byproduct of diketopiperazine. This chemical is made by your body when metabolizing aspartame into the respective amino acids and formaldehyde. Diketopiperazine is a cause for concern because this chemical is implicated in causing brain tumors, especially when consumed from liquid products. Liquids that contain aspartame that are stored for long periods can have an increase in diketopiperazine levels. James Gurney, a researcher investigating brain tumor incidence, states brain tumors in both children and adults have increased since the release of aspartame in the 1980s, but concludes after review of multiple studies that the occurrence of brain tumors caused by aspartame is unlikely. When consumed in moderation, aspartame doesn't pose a threat to the development of brain tumors in children.
Nerve Cell Death
Excitotoxins are chemicals that stimulate your nerve cells to fire continuously, and can cause premature death. Aspartic acid found in aspartame turns into a nerve cell stimulator with glutamic acid that is circulating around the blood. According to Dr. Mercola, 75 percent of the neurons are killed before chronic disease is noticed and diagnosed. This is critical for children because the blood brain barrier that usually protects an adult brain from exocitoxins is not developed enough in children. Higher levels of glutamate and aspartic acid in children's brains could lead to heightened brain activity in children, thus causing behavioral problems.
Depression
Phenylalanine is the other component of aspartame that may predispose children to mood disorders. Phenylalanine accumulates in the blood of persons without phenylketonuria, which is a genetic disorder where phenylalaine isn't broken down and collects in the brain. According to Dr. Mercola, phenylalanine, when combined with carbohydrates, can increases the blood and brain levels of the amino acid in persons without phenylketonuria. Increased phenylalanine levels interupt serotonin levels, causing depression.
References
- "Aspartame Consumption in Relation to Childhood Brain Tumor Risk: Results From a Case--Control Study"; James G. Gurney, Janice M. Pogoda, Elizabeth A. Holly, Stephen S. Hecht, Susan Preston-Martin; 1997
- Mercola.com: Aspartame
- Aspartame Information Center: FAQ
- Dr. Paul: Aspartame and Other Chemical Additives not Necessarily Always Safe



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