Prempro, by Wyeth Pharmaceuticals, is an oral hormone therapy medication available by prescription to treat moderate to severe symptoms of menopause. According to Drugs.com, the medication contains a combination of estrogens and progestin. Women who have not had a hysterectomy and are experiencing natural menopause may benefit from Prempro hormone therapy. Symptoms that Prempro can reduce include hot flashes, night sweats and vaginal discomfort. As with any medication, Prempro has the potential for side effects.
Common Side Effects
According to Drugs.com, most women have few to no side effects when using Prempro. The most common side effects are considered harmless but if they are persistent or bothersome, contact your medical professional. Drugs.com points out the following common side effects: abnormal hair growth; bloating; breast tenderness or pain; changes in sleep patterns; darkening of the skin; dizziness; fatigue; hair loss; headache; irritability; changes in sex drive; lightheadedness; nausea; stomach cramps; stomach upset; and changes in weight.
Serious Side Effects
The risk of severe side effects is quite low but if these symptoms occur, medical attention is necessary. Examples include: breast lumps; swelling in the calf; pain in the calf; breakthrough bleeding; spotting; prolonged bleeding; pain in the chest; weakness; faintness; mood changes; depression; shortness of breath; slurred speech; vision changes; sudden severe headache; swelling of the hands or feet; unusual vaginal discharge, itching, or odor; or jaundice.
According to RxList.com, Prempro should be taken at the lowest effective dose possible for the shortest amount of time. This can decrease the risk of long term side effects of estrogen therapy.
Other Side Effects
According to Prempro.com, estrogen therapy has shown to increase the chance of getting cancer of the uterus. Vaginal bleeding after menopause has been completed can be a sign of uterine issues. Using estrogens can also increase the risk of heart attacks, strokes, breast cancer and blood clots, according to RxList.com. The risk of getting dementia may also increase, explains Prempro.com.
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