5 Things You Need to Know About Trazodone

1. Done With Depression

Trazodone is an oral antidepressant, primarily used to treat depression; however, some doctors also prescribe Trazodone to treat anxiety, chronic pain, alcoholism, panic disorder and insomnia. Trazodone is often marketed under the brand name Desyrel. Trazodone has both sedative and antidepressant effects.

2. Take It the Right Way

Before starting Trazodone, tell your doctor about all medications you're currently taking. Some of the medications that may interact negatively with Trazodone include MAO inhibitors, certain seizure medications, certain antibiotics, Coumadin, digoxen and some HIV medications. It's best to take Trazodone at the same time every day, usually with food. Sometimes, doctors recommend taking Trazodone at night, if it causes increased drowsiness. Limit alcohol intake to avoid excessive drowsiness and dizziness. Until you know the effects of Trazodone on your body, restrict your driving or other activities that require you to be alert and coordinated. If you miss a dose of Trazodone, take it as soon as you remember; however, just skip the dose if you're close to your next scheduled dose.

3. Helps On the Way

One of the benefits of Trazodone is the fact that it works a little more quickly than most antidepressants. Typically, people notice some effects within two or three weeks; however, it may take up to four weeks before it fully takes effect. Your doctor may tweak dosing slightly to achieve desired effects. Don't stop taking Trazodone unless directed to do so by your doctor, since cessation of this medication may lead to withdrawal effects, such as headache, fatigue and dizziness.

4. Concerns for Women and Children

There is not enough substantial research to prove the safety of Trazodone during pregnancy. Pregnant women should only take Trazodone when absolutely necessary. Trazodone does secrete into breast milk, so women who are breastfeeding should consult with their doctors before taking it. Use caution when taking Trazodone under the age of 18, since there isn't enough research to establish its safety and efficacy. Sometimes children and adolescents experience an increase in suicidal thoughts when taking antidepressants.

5. Here Are the Negatives

Side effects of Trazodone range from mild to severe. Common side effects include nausea, dizziness, fatigue, insomnia, irritability, headache, dry mouth, constipation, blurry vision and confusion. More serious side effects, that warrant immediate attention from the doctor, include fainting, fever, flu symptoms, chest pain and difficulty urinating. Some people experience side effects related to sexual dysfunction including a reduced libido and difficulty achieving orgasm. Finally, Trazodone may lead to priapism, a condition in which the penis or clitoris remain erect for an extended period of time. Some cases of priapism have required surgical intervention and have lead to permanent sexual dysfunction.

Last updated on: Nov 18, 2009

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