Introduction
Imitrex, also known as sumatriptan, is a prescription medication that has been specifically developed to help relieve the pain and side effects that come with migraines. Although it's prescribed to help with the pain associated with migraines, it may also help with the nausea, vomiting and sensitivity to light and sound that are commonly associated with a migraine attack.
Cause of Migraines
Migraines can be set off by a multitude of triggers, each varying from person to person. Migraine pain occurs when serotonin levels drop, altering the way your trigeminal nerve operates. This change can cause the release of neuropeptides, which travel to the meninges of the brain. Once the meninges are stimulated, migraine pain occurs.
How it Works
Imitrex is most commonly taken orally, or in cases of serious headaches may be injected. This medication works by targeting serotonin receptors of the brain. The stimulating of these receptors causes the muscles around the blood vessels of your brain to contract. The contraction of these muscles forces the blood vessels to constrict, which changes the way the blood flows. This change in blood flow prevents the release of the neuropeptide substance P. Without substance P, the meninges aren't affected, and the pain from the migraine subsides.
Side Effects
Patients taking antidepressants, ulcer medications, beta blockers or any medications containing the ingredient ergot should talk to their doctor before being put on Imitrex, as serious complications may occur when the medications are combined. Imitrex may also come with mild side effects that include drowsiness, flushing, muscle aches and nausea. In very rare cases, chest pain, irregular breathing and convulsions may occur, in which case medical attention should be sought immediately.



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