Major depressive disorder affects more than 14 million American adults, and is more common in women then men, according to the National Institute of Mental Health. Depression is characterized by a feeling of sadness that is intense enough to affect daily activities. Changes in appetite, weight and sleep are also common in depression. Flax is a plant native to Asia that produces seeds rich in essential fatty acids omega 3 and 6. According to research studies, omega 3 fatty acids from flax seeds can improve symptoms of depression. Talk to your doctor before taking flax oil or any other supplements.
Research
Clinical research suggests that omega-3 fatty acids are a potential treatment of depressive disorders, but not for mania, says N.V. Kraguljav, MD from the Mayo Clinic College of Medicine, based on a systematic review of clinical studies that evaluated the link between omega 3 fatty acids and mood disorders. The study was published in 2009 issue of " Psychopharmacology Bulletin." Larger trials are needed to better assess the value of flax oil supplementation for patients with depression.
How it Works
Flax seed oil contains omega 6 fatty acids such as linoleic acid and omega 3 fatty acids such as alpha linolenic acid, or ALA. EPA, or eicosapentaenoic acid and DHA, or docosahexaenoic acid, are two essential fatty acids formed in the body from alpha linoleic acid.
K.Ohara, MD, from Shinshiro Municipal Hospital explains in a study published in 2005 issue of " Psychiatrica and Neurologica Japonica" that the peripheral blood levels of omega 3 fatty acids are decreased in patients with major depression.
Sources of omega 3 fatty acids are flax seed oil, walnuts, canola oil and fatty fish. While supplementation with omega 3 fatty acids may benefit individuals with depression, it is the EPA that is useful in treating this condition. However, notes Ohara, further research on omega 3 fatty acids is needed to assess their benefits in mood disorders.
Safety
Flax oil is generally safe in doses up to 50 g a day and is well tolerated. However, it is not recommended during pregnancy and lactation, according to Drugs.com. Flax seed oil may also cause allergic reactions in susceptible individuals. Although no clinical cases of drug interactions have been reported, theoretically, flax seed oil may interfere with blood thinners, mood stabilizers, drugs prescribed for high cholesterol and high blood pressure, says Drug.com.
Considerations
Consult a health care provider to find out optimal dosage of flax seed oil for your condition. Keep in mind that flax seed oil or other supplements do not replace any conventional drugs that you are currently taking.
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