Behavior in manic depression, or bipolar disorder, is generally split between depressed moods and bouts of mania that are unpredictable and do not always respond to nutritive methods. However, several supplements on the market can help decrease symptoms. To find out which supplements are best for your manic depression, it is imperative to consult with a licensed health professional familiar with your condition.
N-Acetylcysteine
N-acetylcysteine is an amino acid necessary for the production of glutathione, which is often deficient in individuals with manic depression. Glutathione is an antioxidant in cells that helps eliminate toxins from the body and most importantly from the brain. Glutamate is a neurotransmitter that is often found in abundance in individuals with mood disorders like manic depression, and glutathione works to keep this balance in check. Supplementation of n-acetylecysteine should not exceed 2 g in a daily dose, unless otherwise directed by a doctor.
Choline
Choline is an essential nutrient found in phosphatidylcholine, or lecithin. The body can produce small amounts, but the primary source of choline must come from diet or supplementation. In individuals with manic depression, choline may be lacking in the body, resulting in drastic mood shifting. According to PsychCentral.com, manic depressive individuals can find calmness and balance in moods from supplements. In the form of lecithin, this product is manufactured in both capsule and granule form that can be added to food and beverages. Dosing can range from 2,000 to 7,000 mg and should be supervised by a licensed health practitioner.
Omega-3s
Omega-3s are essential fatty acids that are not produced by the body and must be supplied by the foods we consume or supplementation. For those with manic depression, diets high in oily fish, plants and nut oils may be recommended. In addition to changes to diet, "Nutrition Journal" posits that supplements have yielded positive results when compared with valproate and lithium pharmacologic treatments in clinical trials with manic depressives. The dose can vary between 3 and 9 g per day and should be used as an adjunct treatment to psychotropic medication for best results.
B Vitamins
The B vitamins are heralded for their ability to metabolize food, regulate moods and put a little pep in your step. For individuals who suffer from primarily depressive symptoms, the vitamin B complex may be helpful. According to an article in "Psychology Today," B vitamins -- especially B12 -- have continued to show tremendous progress in lifting depressed moods in clinical trials. The B vitamins may play a key role in clearing the body of harmful homocysteine levels that damage the heart and can result in stroke. In addition, this vitamin provides a boost to the ability to experience pleasure thanks to its role in producing the neurotransmitter dopamine. Vitamin B complex should be taken as directed on the label as an adjunct to existing pharmacological treatment.
References
- Bipolar News network: The N-Acetylcysteine Story: A New Potential Therapy for Bipolar Illness and Substance Abuse
- PsychCentral.com; Nutritional Supplements for Bipolar Disorder
- "Nutrition Journal"; Omega 3 Fatty Acids Decreased Irritability of Patients with Bipolar Disorder
- "Psychology Today"; Vitamins, Get Your Bs
