Cholesterol is a lipid that is essential for several functions in the body, including vitamin D synthesis and hormone production. However, excess low density lipoprotein, or LDL cholesterol, can be deposited in artery walls, thereby increasing the risk for heart disease. Evidence suggests that coffee contains compounds that may increase LDL cholesterol levels in the body.
Cafestol
Regular and decaffeinated coffee contains the compound cafestol, which might elevate LDL cholesterol levels in the body, according to a study conducted by Dr. David Moore and researchers from Baylor College of Medicine. Scientists discovered that cafestol attaches to a receptor in the intestine and prevents it from regulating cholesterol levels. This in turn increases LDL cholesterol levels in the blood. Researchers reported their findings in the July 2006 issue of the "Journal of Molecular of Endocrinology."
Kahweol
Kahweol, a lipid compound found in coffee, might increase cholesterol levels, according to researchers from the University of Osio. Similar to cafestol, kahweol reduces the activity of receptors that help regulate cholesterol levels in the body. This results in an accumulation of LDL cholesterol, the October 1997 issue of the journal "Arteriosclerosis, Thrombosis, and Vascular Biology" reports.
Increases Cholesterol Levels
Researchers from Yonsei University Graduate School of Health performed a review of clinical studies regarding the relationship between coffee consumption and cholesterol levels. The report, which was published in the February 2001 issue of the "American Journal of Epidemiology," concluded that coffee increases cholesterol levels in a dose-dependent matter, especially for individuals suffering from high cholesterol levels.
Side Effects and Interactions
In addition to raising cholesterol levels, too much coffee can cause nervousness, tremor, headache, nausea and vomiting due to its high caffeine content. Furthermore, coffee can interact with certain medications, according to the Linus Pauling Institute at Oregon State University website. Therefore, consult your health-care provider before drinking coffee, especially if you have high cholesterol or are taking any medications.
References
- Science Daily: How Coffee Raises Cholesterol
- Arteriosclerosis, Thrombosis, and Vascular Biology: Effect of Coffee Lipids (Cafestol and Kahweol) on Regulation of Cholesterol Metabolism in HepG2 Cells
- PubMed.gov: Coffee consumption and serum lipids: a meta-analysis of randomized controlled clinical trials
- Linus Pauling Institute: Coffee


