Lysine is an essential amino acid which is not produced by the body and must be obtained by eating lysine-rich foods such as red meats and dairy products, or by taking a supplement. Although not approved by the U.S. Food and Drug Administration, many use lysine to help prevent cold and genital herpes outbreaks, to manage symptoms of Bell's palsy, and to prevent osteoporosis-related bone loss. Before embarking on lysine therapy, it is wise to understand the risks and to consult your doctor.
Health Concerns
Although lysine is an essential part of the diet, the safety of concentrated lysine supplements has not been well studied. In animal studies, high dosages have caused gallstones and elevated cholesterol levels, according to the Virginia Hospital Center. For this reason, it is important to check with your doctor if you have a history of gallstones, high cholesterol, kidney or liver disease.
Arginine and Lysine
Arginine is another essential amino acid that shares the same bodily pathways as lysine. For this reason, scientists speculate that high levels of arginine may inadvertently work to lower lysine levels in the body. As a precaution when taking lysine, take care not to take arginine supplements, and be sure to eat a diet that does not contain large amounts of arginine-rich foods such as chocolate and peanuts.
Aminoglycosides Toxicity
According to Drugs.com, there are a handful of drugs which may become toxic when taken with lysine. They include aminoglycosides, a group of antibiotics effective against certain types of bacteria. Examples of animoglycosides include gentamicin, tobramycin, amikacin, kanamycin, netilmicin, neomycin and streptomycin.
Side Effects
Lysine appears safe for most people for a period lasting as long as a year, according to RxList. While side effects are mild, high doses between 15 and 40 g per day can lead to stomach pain and diarrhea.
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