According to the experts at the Mayo Clinic, butorphanol is a pain reliever that is available by prescription only. It comes in both a nasal spray form and in an injectable form; the prescription you receive will be determined by you and your doctor. Although there are two separate means of delivery, the side effect profiles are the same.
Common Side Effects
These common side effects generally don't require medical attention. They include confusion, dizziness, dry mouth, headache, loss of appetite, nausea and/or vomiting, insomnia, weakness (sometimes severe), constipation, drowsiness, flushing (hot flashes), nasal congestion, perspiration and an unpleasant taste in your mouth.
Less Common Side Effects
The doctors at Mayo Clinic state that you may also experience less common side effects which are still not considered serious, yet are considered to be rare. These include feeling anxious, a burning or prickling feeling on your skin, feeling hot or warm, being nervous, experiencing stomach pains, trembling, changes in your behavior, feeling as though you are floating, a pounding heart and having strange dreams.
Serious Side Effects
Serious side effects should be reported to your doctor as soon as possible. These include difficulty breathing, nose bleeds, runny nose, sneezing, fever, ears ringing, sore throat, blurred vision, cough, painful breathing, fainting, itching, hives, chest congestion, problems urinating, ear ache and hallucinating.
Signs of Overdose
Overdose is possible with butorphanol. If it occurs, emergency medical assistance is required. The signs to watch for include cold or clammy skin, seizures, severe dizziness or drowsiness, small pupils, slowed breathing or heart rate and loss of consciousness. An overdose can be fatal; if you recognize any of these signs in someone, call 911 immediately.



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