Is Too Much Vitamin B12 Harmful?

Your body relies on vitamin B-12 to produce red blood cells and maintain proper brain function. Adults should consume between 2.4 and 2.8 mcg of vitamin B-12 each day to keep their bodies healthy, according to the Office of Dietary Supplements. The primary sources of vitamin B-12 include certain foods, such as fish and beef, and dietary supplements. If you take a vitamin B-12 supplement, be sure to only use this supplement as directed to limit your risk of developing unusually high vitamin B-12 blood levels.

Overdose Symptoms

Vitamin B-12 is a water-soluble nutrient and is typically non-toxic to your body -- even when it's present in high levels. Unlike fat-soluble vitamins, water-soluble vitamins are not retained or stored in your body's fat tissue. Instead, your body simply absorbs the amount of vitamin B-12 it needs and removes the remaining vitamin B-12 from your body in the form of urine. Consequently, there are no symptoms or side effects specifically related to taking too much vitamin B-12, the Linus Pauling Institute explains; however, if you experience any unusual medical problems after taking a high dose of vitamin B-12 consult your physician for further evaluation and care.

Mild Side Effects

Mild side effects including diarrhea and skin rash may occur during treatment with any dosage of vitamin B-12 supplements. Discuss chronic diarrhea with your doctor as this side effect may cause dehydration. Symptoms associated with dehydration include dizziness, excessive thirst, fatigue and headache.

Medication Interactions

Before taking vitamin B-12 supplements, be sure to discuss all medications you are currently taking with your primary medical provider. Concomitant use of vitamin B-12 and tetracycline, a specific type of antibiotic, should be avoided, the University of Maryland Medical Center warns. Vitamin B-12 may prevent your body from absorbing tetracycline, which can reduce the efficacy of this antibiotic.

Contraindications

If you have any pre-existing health problems, be sure to let your doctor know before you begin treatment with vitamin B-12 supplements. Additionally, do not take this supplement if you are allergic to vitamin B-12, cobalt or cabalamin, MayoClinic.com warns. Hypersensitive people who use this natural supplement are at risk of develop a severe allergic reaction called anaphylaxis. An anaphylactic reaction requires emergency medical care and may cause breathing problems, difficulty swallowing, hives, weakness or facial swelling.

References

Article reviewed by Jenna Marie Last updated on: Jan 20, 2011

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