Papaya enzyme, also called papain, comes from the milky juice of papaya fruit. Herbalists have used papain to treat various illnesses, especially those associated with digestion, RxList.com reports. The enzyme also may help if you suffer from herniated discs. Before trying herbal supplements that have not yet been approved by the U.S. Food and Drug Administration, such as papaya enzyme, talk with your doctor . You may experience side effects if you use papaya enzyme supplements.
Severe Gastritis
Severe gastritis may occur as a side effect of taking papain, Drugs.com indicates. This means you may feel sick to your stomach. Although this herbal supplement is purported to help with digestive problems, you may still experience this side effect, particularly when you start ingesting papaya enzyme. If this side effect does not go away when your body grows accustom to the supplement, you contact your doctor for help.
Slow Heart Rate
Your heart rate may slow, a condition known medically as bradycardia, because you are taking this supplement, Drugs.com states. A slow heart rate may reduce the amount of oxygen reaching your extremities and your brain. You may feel cold in your feet and hands, and you may become confused without sufficient oxygen in your brain. Contact your doctor if your heart rate does not pick up and go back to its normal rate.
Paralysis
You may experience paralysis in any part of your body from using papaya enzyme supplements. This side effect needs medical attention because the paralysis could occur in your respiratory center, meaning your lungs will not function properly, making it difficult for you to breathe. This requires a visit to the emergency room immediately. You need a medical evaluation and possible treatment if you experience this side effect.
Esophageal Perforation
Esophageal perforation is a serious condition that requires hospitalization and emergency surgery. Papain may cause a hole to develop in your esophagus, Drugs.com indicates. Medical advice remains important when considering supplements.
Nervous System Problems
Decreased central nervous system activity may occur as a side effect to the enzyme inside the papaya, Drugs.com reports. You may respond more slowly to stimulation from verbal contact or to normal situations that usually require your attention. If you experience this side effect, you should not drive a vehicle. Get help from a doctor as soon as possible at the emergency room. A change in central nervous system response is unpredictable and needs medical treatment.



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