Coenzyme Q-10 is a chemical similar to vitamins involved in several biological processes in the body, particularly in the liver, kidneys, heart and pancreas. Coenzyme Q-10 is frequently taken to treat a variety of medical conditions, including heart disease, diabetes and high blood pressure. Although coenzyme Q-10 is generally safe and well-tolerated, in some cases, it may cause side effects, including side effects that resemble flu symptoms. As with any health supplement, you should consult your doctor before taking coenzyme Q-10.
Flu-Like Symptoms
Side effects resembling flu symptoms can occur after taking coenzyme Q-10. These can include nausea and vomiting, which are often accompanied by a decrease in appetite. Diarrhea as well as abdominal discomfort or pain, particularly epigastric, or upper abdominal pain, can also occur. Headache, heartburn and fatigue are also possible.
Additional Side Effects
Coenzyme Q-10 may also result in additional side effects, including irritability and photophobia, which is an increased sensitivity to visual stimuli. Dizziness and skin rashes are also possible. In some people, coenzyme Q-10 can lower blood pressure, which can be particularly dangerous for people with already low blood pressure.
Drug Interactions
Several medications can possibly interact with coenzyme Q-10. Because coenzyme Q-10 lowers blood pressure, people taking blood-pressure lowering medications should use extra caution when taking coenzyme Q-10. The effectiveness of certain cancer medications may be decreased by coenzyme Q-10, due to its antioxidant properties. Coenzyme Q-10 increases blood-clotting, which may decrease the effectiveness of blood-thinning medications like warfarin. In patients with diabetes, taking coenzyme Q-10 may decrease the dose of insulin needed.
Dosage
Coenzyme Q-10 has been tested for toxicity at doses up to 1200 mg for day for periods as long as 16 months, with no significant risk of serious adverse events, reports the Linus Pauling Institute at Oregon State University. Doses of 600 mg have been tested for even longer -- up to 30 months -- and found to be safe. If you are experiencing side effects from coenzyme Q-10, breaking the dose into several smaller doses and taking those at different times throughout the day may decrease the risk of side effects.
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