Alli is an over-the-counter medication that is used to facilitate weight loss along with a diet and exercise plan and healthy lifestyle changes. Metformin is an oral prescription medication that is used to treat type 2 or non-insulin dependent diabetes mellitus. The primary use of Alli is to shed pounds in individuals that may be overweight or obese. A side effect of metformin in some individuals is also weight loss. Hence, taking Alli along with this medication requires the supervision of a doctor.
The Use of Alli
According to the MayoClinic.com, Alli is a reduced strength version of the prescription obesity drug orlistat, which is sold under the brand-name Xenical. Alli contains 60 milligrams of orlistat while Xenical contains 120 mg. Alli is meant to be used in combination with a low-fat and low-calorie diet and regular exercise, for healthy weight loss.
How Alli Works
The medication Alli promotes weight loss by reducing absorption of fat by the intestines so that fewer calories are stored in the body. It works by disabling the enzyme lipase, which is found in the digestive tract and is necessary for digesting dietary fats. The undigested fat is then passed through the intestines and eliminated in bowel movements. The recommended dose of Alli is one tablet up to three times a day, taken before meals. To reduce side effects such as urgent bowel movements, diarrhea and gas, it is recommended to consume 15 grams of fat or less in each meal.
How Metformin Works
Metformin is taken once a day for the treatment of diabetes and pre-diabetes, a condition in which blood glucose levels are consistently too high. It works by facilitating the transport of dietary glucose from the blood into the tissues of the body and by decreasing the amount of glucose absorbed from the intestines and released from the liver.
Metformin and Alli
The pharmaceutical effects of the drug metformin can result in side effects including weight loss and decreased hunger, which is especially beneficial for overweight or obese people with diabetes. However, too much weight loss can be dangerous. Therefore, the use of Alli and other diet aids for weight loss should be used only with the recommendation and guidance of a doctor, particularly if the individual is also taking metformin or other medications for the treatment of diabetes.



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