Creatine is an amino acid naturally produced in the body that is stored in the muscles and used for energy. According to the University of Maryland Medical Center, creatine supplements have increased in popularity because of its possibility to increase lean muscle mass and enhance athletic performance. There are side effects to using creatine supplements, some of which can be serious. Prior to using creatine supplements, consult with your health care provider to learn whether this supplement is safe for you to take.
Muscle Reactions
Creatine can cause muscle breakdown and cramps, which can lead to tearing of the muscles or discomfort, reports MayoClinic.com. There have been reports of muscle strains after taking creatine due to increases in workout routines, so it is best not to alter your workout regimen too quickly. Weight gain and increased body mass have also been reported. Rxlist.com adds that creatine causes your muscles to take water from other parts of your body, so you should drink extra water when taking this supplement, and do not workout in the heat, as this can increase your dehydration.
Drug Interactions
Creatine has the potential to interact with a range of medications, including non-steroidal anti-inflammatory drugs, diuretics, Tagamet, and probenicid, says the UMMC. Caffeine may also interact with creatine and can increase the risk of dehydration, and using caffeine, creatine and ephedra can increase the risk of stroke, says the university.
Effects on Insulin
MayoClinic.com states that individuals with diabetes or hypoglycemia, as well as those taking any drugs or supplements that alter blood sugar should use creatine with caution, since it may affect insulin in the body. Glucose levels may need to be monitored extra closely or under the supervision of a health care professional, so medication or insulin dosages can be adjusted
Other Side Effects
Other side effects have been reported in individuals taking creatine, including loss of appetite, diarrhea, nausea, stomach pain, thirst, headache, aggression, depression, abnormal heart rhythm, fainting and dizziness, says MayoClinic.com. More side effects include an increased risk of blood clots in the legs and seizures. The UMMC states that people have also experienced high blood pressure, liver dysfunction and kidney damage. Individuals with kidney or liver disease should not take this supplement, says MayoClinic.com, due to alterations in kidney and liver functioning that this supplement may cause.
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