Nutritional Supplements for Alzheimer's Disease

Nutritional Supplements for Alzheimer's Disease
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Alzheimer's disease is a progressive neurological disease of the brain characterized by impairment in memory, judgment, decision making, orientation to physical surroundings, and language. The exact cause is unknown, and there is currently no cure for this disease; however, certain nutritional supplements may support brain health and slow down its progression. Some supplements are toxic in high doses; you should consult your health care practitioner before taking any new supplement.

Phosphatidyl Serine

Phosphatidyl serine is a chemical that is found naturally in the brain, and supplements of it are derived from soy. Although more research still needs to be done to confirm its efficacy, the Canadian School of Natural Nutrition, or CSNN, says that taking a phosphatidyl supplement has been found to be beneficial to Alzheimer's sufferers. Alzheimer's Association explains that it is purported to protect brain cells from degeneration. CSNN adds that clinical studies have found it to improve mental function, mood and behavior in Alzheimer's patients. As such, CSNN says to take 100 mg, three times daily with food.

Trimethylglycine

Trimethylglycine, or TMG, helps to reduce toxic elements in the body, such a homocysteine. This is important because these elements have been implicated as contributors to Alzheimer's disease. In addition, TMG has been found to elevate the mood of Alzheimer's sufferers. It also helps the body to properly absorb and utilize vitamins B6, B12 and folic acid, which are three important vitamins for healthy brain function, according to Phyllis Balch, in "Prescription for Nutritional Healing." Balch therefore recommends taking 500 to 1,000 mg of TMG daily, in the morning.

Antioxidant Supplements

Selenium, pycnogenol, grape seed extract and Coenzyme Q10, are all powerful antioxidants. Supplementing with one of these nutrients can help to increase oxygen delivery to the brain, and protect the brain cells from free radical induced damage (see reference 1, page 170-171). For therapeutic purposes, take one of these supplements daily, as directed on the bottle, or consider buying a mixed antioxidant supplement that contains a blend of these antioxidants.

Acetyl-L-carnitine

Acetyl-L-carnitine, is an amino acid that is produced in the body naturally, and supplements of it are used for a variety of mental disorders including Alzheimer's disease. Balch says that it supports healthy brain function and may help to slow down deterioration of memory. It also acts as an antioxidant and helps to reduce oxidative damage to the brain. For therapeutic purposes, Balch says to take 500 mg of acetyl-L-carnitine, twice daily, between meals.

Fish Oil

A fish oil supplement may also be beneficial, due to the omega-3 essential fatty acids EPA and DHA, found in fish oil. Supplementing with omega-3s may help to reduce inflammation and protect brain cells from damage. As such, CSNN recommends taking a fish oil supplement that contains 1 to 2 g of combined EPA and DHA, daily. Alzheimer's Association warns however, that there is not yet enough conclusive evidence to support the use of fish oil for Alzheimer's treatment.

References

Article reviewed by Gina Skurchak Last updated on: Feb 8, 2011

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