The estrogen ring or estradiol vaginal ring is used as a replacement for estrogen in post-menopausal women. The estrogen ring is marketed by Pfizer under the brand name Estring. The ring is helpful in relieving vaginal problems associated with the reduction of estrogen after menopause. Symptoms that may be relieved include vaginal dryness, burning, itching and painful intercourse. As with any medication, the estrogen ring has the potential for side effects. Call your doctor if you develop any worrisome side effects.
Common Side Effects
Most women do not experience any side effects with the use of the estrogen ring, according to Drugs.com. According to Pfizer, an increase in vaginal secretions is common and is a positive effect of the medication. If the secretions are associated with a bad odor, itching or other signs of vaginal infection, Pfizer recommends medical treatment. Vaginal discomfort, abdominal pain and genital itching may occur, but they are not considered acceptable side effects of the medication. Other common effects, according to Pfizer, include headache, breast pain, irregular vaginal bleeding or spotting, abdominal cramps and bloating, nausea and vomiting, hair loss, fluid retention and/or vaginal yeast infection.
Less Common Side Effects
Pfizer suggests women may be at risk of toxic shock syndrome (TSS). This syndrome is the result of a bacterial infection that leads to fever, nausea, vomiting, diarrhea, muscle pain, dizziness, faintness and a red rash on the face and body. Drugs.com reports other side effects to be arthritis, back pain, flu-like symptoms, joint pain, sinus inflammation and an upper respiratory tract infection.
Serious Side Effects
In very few cases, the vaginal ring can become attached to the vaginal wall, making removal difficult. The use of estrogen therapy has been linked to the increased risk of breast cancer, cancer of the uterus, stroke, heart attack, blood clots, dementia, gallbladder disease, ovarian cancer, high blood pressure, liver problems, high blood sugar and the enlargement of tumors in the uterus, according to Pfizer.com.
