Humalog is the brand name of insulin lispro, which is a rapid-acting insulin. Insulin lispro is a hormone used in type 1 and type 2 diabetes to control blood sugar levels. Insulin is necessary to break down carbohydrates, fats and proteins from the food you consume. Individuals with type 1 diabetes are not able to produce insulin and require medication, while in type 2 diabetes, individuals do not produce enough insulin and have developed a resistance to the insulin their bodies do produce.
Administration
Humalog is a solution that is injected subcutaneously. It should be injected about 15 minutes before a meal or right after a meal. You may inject the medication into a "meaty" area, such as the arms, thighs or stomach. You can ask your physician or pharmacist to explain how to use this medication properly. Follow directions exactly as directed to avoid an overdose and adverse reactions.
Side Effects
Local reactions at the injection site can include swelling, itching, pain and stinging. Fatigue, headache and nausea are common side effects seen with this drug. Swelling in the feet and legs may occur and should be reported to a health care professional. If any side effect worsens or becomes persistent, speak with your physician as soon as you can.
Warnings
Humalog may produce hypoglycemia, which is low blood sugar, and all patients should be educated properly. Signs and symptoms of hypoglycemia include hunger, irritability, trembling, headaches, seizures and eventually coma and death. If you are on insulin, you should document how often hypoglycemia occurs, especially if it involves the assistance of another person, emergency care, or hospitalization. Skipping meals and exercising vigorously may increase the risk of experiencing hypoglycemia. If you develop signs and symptoms of hypoglycemia, seek medical attention right away. Do not use Humalog if you check your glucose and it is low.
Humalog can cause a shift in the movement of potassium in the body and may produce a low potassium level, known as hypokalemia. Hypokalemia may cause irregular heartbeat, collapse of the lungs and death. Your physician should monitor your potassium level regularly to make sure it is within normal range; if the level is low, you may require potassium supplements.
Dosage Adjustment
Individuals with kidney impairment may require a lower dose due to a slower removal from the body. Your physician will monitor your levels closely and adjust the dose accordingly. Patients with live impairment may break down the medication at a slower rate and may also require lower doses of Humalog.
References
- PubMed Health: Insulin Lispro Injection
- "Pharmacotherapy: A Pathophysilogic Approach"; Joseph T. DiPiro, Robert L. Talbert, et al.; 2008
- "Drug Information Handbook"; Charles F. Lacy, Lora L. Armstrong, et al.; 2009
