An essential amino acid required in the human diet, lysine serves as one of the crucial building blocks of proteins in your body. Consuming lysine-rich foods such as meat, nuts, fish and eggs or lysine supplements can help you get the 12 mg/kg of body weight recommended by the University of Maryland Medical Center each day. Lysine supplements may also be used to control cold sore outbreaks caused by the herpes simplex virus. Be sure to discuss the safety issues associated with lysine supplements before you begin this type of treatment.
Mild Side Effects
When used as directed, lysine supplements are deemed safe for most people for up to one year of daily treatment. However, mild side effects may occur when taking lysine. You may experience mild stomach pain or irritation, which can lead to diarrhea or loss of appetite. Loose bowel movements may be bothersome and may occur together with cramping or bloating. Talk with your doctor if such side effects persist, as chronic diarrhea may increase your risk of dehydration.
Severe Side Effects
Health professionals with the University of Maryland Medical Center warn that taking more than the recommended dose of lysine may cause gallstones. Gallstone symptoms may be severe and can include sudden abdominal, back or jaw pain. These symptoms may be so intense that you have difficulty sitting still or falling asleep. Gallstones may also cause complications, including fever, chills or jaundice -- a condition characterized by abnormal yellowing of the whites of your eyes or your skin. Seek prompt medical care if gallstone symptoms arise to ensure that you receive appropriate treatment.
Interactions with Medications
Lysine supplementation may not be safe if you are taking certain medications. Always inform your doctor of any medication or supplement you are using before beginning treatment with lysine supplements. Do not use lysine supplements in conjunction with calcium supplements unless otherwise instructed by your doctor. This combination of supplements may significantly increase your blood levels of calcium -- a serious health condition called hypercalcemia. Hypercalcemia may cause weakness, fatigue, weight loss, nausea, kidney stones and organ or tissue calcification.
Contraindications
If you have certain health concerns or problems, lysine supplementation may not be right for you. Do not take lysine supplements if you are pregnant or breastfeeding without first consulting your doctor. Additionally, avoid using lysine supplements if you have a personal history of kidney or liver problems, as this natural supplement may exacerbate your health condition.
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