Potassium citrate is often used to treat a kidney condition called renal tubular acidosis. Renal tubular acidosis occurs when the kidneys cannot filter acids from the blood, causing the blood to remain overly acidic. Too much acid in the blood promotes the development of kidney stones. Potassium citrate decreases the aciditypf the blood as well as urine.
Dosage
The proper dosage for potassium citrate depends on the specific condition and the form of the supplement. Liquid potassium citrate should be mixed with at least 4 oz. of water or juice. You should consume the mixture slowly, over a period of 5 to 10 minutes, according to Drugs.com. Potassium tablets or extended-release capsules should be taken with at least 8 oz. of water. You should always take potassium citrate with a meal or a snack, or within 30 minutes of consuming a meal. You should also avoid lying down for at least 30 minutes after taking potassium citrate.
Side Effects
Regular use of potassium citrate has the potential to cause some side effects. Most of the common side effects are not serious. Common side effects include diarrhea, nausea, vomiting, stomach pain, gas and bloating. Some more serious, but less common side effects include shortness of breath, difficulty breathing, anxiety, fatigue, weakness, confusion, irregular heartbeat and numbness or tingling in the hands, feet and lips. Rare side effects include abdominal pain, stomach cramps, chest pain, throat pain and bloody stool. If you experience any of these side effects, you should contact your doctor immediately.
Warnings
If you have kidney failure, a urinary tract infection, peptic ulcer disease, Addison's disease or uncontrolled diabetes, you should not take potassium citrate. You should also avoid potassium citrate if you are dehydrated or take diuretics, as the combination can lead to dangerously high levels of potassium in your blood, a condition known as hyperkalemia.
Considerations
Your doctor may recommend a specific diet for you to follow while taking potassium citrate. It is important to closely follow any dietary recommendations to avoid serious side effects. While taking potassium citrate, you should also avoid taking any other potassium supplements or consuming salt substitutes, which often contain potassium.



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