Conjugated linoleic acid is a polyunsaturated fatty acid found naturally in beef and dairy products. Supplemental forms of conjugated linoleic acid may yield health benefits when used medicinally. Purported health benefits include reduced cholesterol, weight maintenance and cancer treatment and prevention. However, additional clinical research in humans is necessary to validate these potential medicinal uses of conjugated linoleic acid. Before adding this supplement to your daily regimen, talk with your doctor about conjugated linoleic acid supplement safety.
Mild Side Effects
Conjugated linoleic acid typically doesn't cause adverse side effects when used as directed. Mild stomach irritation may occur after you take a dose of this supplement, and it may cause nausea or stomach pain. Diarrhea may also occur, which may contribute to abdominal cramping or bloating. You may feel unusually fatigued while taking conjugated linoleic acid. Increased fatigue may make it harder for you to pay attention or remain active during your normal daily activities. Consult your primary medical provider if these mild side effects persist or become severe.
Severe Side Effects
A study cited by the University of Michigan Health System says that long-term treatment with this fatty acid supplement may elevate your risk of developing heart disease. If you have a personal or family history of cardiovascular disease, consult your medical provider before using this supplement. Additionally, seek emergency medical care if you experience any symptoms of heart disease or heart attack, including chest tightness or pain, upper-body pain, dizziness, excessive sweating or shortness of breath.
Contraindications
If you have certain health problems, conjugated linoleic acid supplementation may not be appropriate for you. Avoid taking this supplement if you have diabetes. Conjugated linoleic acid may increase the severity of your diabetes symptoms. People with metabolic syndrome should also avoid treatment with conjugated linoleic acid, because this supplement may increase your risk of developing diabetes. Do not use this fatty acid supplement if you are breastfeeding or pregnant. The safety and effectiveness of conjugated linoleic acid have not been evaluated in women during pregnancy.
Interactions with Other Drugs
Inform your physician of any medication or supplement you are taking before you initiate treatment with conjugated linoleic acid supplements. As of January 2011, there are no known drug interactions associated with the use of this supplement.



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