Phentermine hydrochloride first became available in the U.S. in the 1970s and now accounts for 50 percent of all weight loss drugs sold. It is chemically related to amphetamines. Phentermine comes in capsules or extended release tablets and is usually taken for a short duration, depending on response. This drug can be habit forming and must be taken as prescribed.
Mechanisms
Phentermine is in a class of drugs called anorectics and acts partially through appetite suppression. More precise modes of action are unknown but probably involve the central nervous system or other aspects of metabolism.
Lifestyle
Diet and exercise regimens in combination with phentermine improve weight loss.
Mild Side Effects
People may experience an unpleasant taste or dryness in the mouth, diarrhea, constipation, tremors or insomnia.
Severe Side Effects
Less common but more serious side effects include increased blood pressure, heart palpitations, dizziness, shortness of breath, chest pain, edema of the ankles and increased exercise intolerance.
Precautions
Caution is advised in people with high blood pressure or diabetes. Phentermine can impair a person's ability to operate machinery or drive. Safe use in pregnancy has not been established.
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