Urokinase, with is marketed under the brand name Kinlytic, is an intravenous medication designed to break up pulmonary embolisms or blood clots in the lungs. It may be prescribed when you cannot sustain normal blood pressure without help from supportive measures. According to RxList.com, urokinase should be administered as soon as possible to give it the most chance to destroy the embolism.
Typical Side Effects
All reported side effects of urokinase use are potentially serious. Tell your doctor or other medical professional as soon as possible if you experience any side effects from the drug. According to the Mayo Clinic, the more common side effects from urokinase include shortness of breath, bleeding gums, coughs that produce blood, urine discoloration, usually dark brown or red, swallowing problems, black or red and tarry stools, breathing problems, abnormal duration bleeding when you have a cut, dizziness, paralysis, headaches, nosebleeds or menstruation changes such as increased flow or bleeding from the vagina.
Rare Side Effects
Urokinase usage also may produce serious side effects that are rarely reported. Again, if you have any of them, tell your physician. They include wheezing, a cough, abnormal tiredness, rapid heartbeat, abnormal bodily weakness, hives, chest tightness, welts on the skin or itching, a rash on the skin or redness, loud breathing and facial swelling that may be centered on the eyelids, tongue, lips or around the eyes.
Other Side Effects
The Mayo Clinic reports some serious side effects from urokinase that have occurred in patients but without specific numbers or percentages of occurrence. Talk to your doctor about any of them that you may experience. They include unconsciousness, fingernails or lips that turn blue, difficulty walking, vision blurring, difficulty speaking, pain in the chest, discomfort in the chest, ankle or leg swelling, confusion, seizures, arm or leg weakness on the left or right body side that is sudden or severe, rapid breathing, headaches that are sudden or severe, fainting, palpitations, heartbeats that become rapid, irregular or pounding, skin paleness, inability speaking, excessive sweating, tingling or numbness in the extremities or face or hypotension, which is low blood pressure.
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