L-tryptophan is an essential amino acid, which can only be obtained through food. In the body, L-tryptophan is converted to serotonin, an important neurotransmitter involved in mood, sleep and impulse control. According to Nutritional Supplements Health Guide, while L-tryptophan is considered safe, it has not been approved by the FDA. As such, you should not substitute L-tryptophan for medication prescribed by your health care provider.
Depression
Depression is a state of low mood that can affect a person's thoughts, behavior and feelings. A study published in 2001 and conducted at the University of Oxford found that L- tryptophan is more effective than placebo at alleviating depression. L-tryptophan, a natural alternative to traditional antidepressants, works by increasing the levels of serotonin in the brain, which in turn reduces the symptoms of depression.
Sleep Promotion
L-tryptophan may enhance relaxation and sleep, according to Vitamins and Health Supplement Guide. L-tryptophan is important for the production of serotonin in the brain; serotonin is one of the key brain chemicals involved in the body's regulation of sleep. Increasing L-tryptophan through food or supplements may help normalize sleep patterns.
Other Effects
L-tryptophan supplementation may increase serotonin levels in the brain. According to Vitamins and Health Supplement Guide, L-tryptophan supplementation may be helpful for people with migraine headache. Additionally, L-tryptophan may also help relieve minor premenstrual symptoms and menopausal depressive conditions.
Side Effects
L-tryptophan supplements do have multiple side effects along with its needed effects. According to National Eosinophilia-Myalgia Syndrome Network, one of the severe side effects of L-tryptophan is Eosinophilia Myalgia syndrome, a complex systemic syndrome that affects the skin, fascia, muscle, blood vessels, nerve and heart. People taking L-tryptophan may also experience other side effects, which can include nausea, vomiting, headache, dry mouth, and blurred vision.
References
- "Cochrane database of systematic reviews"; Tryptophan and 5-hydroxytryptophan for depression; K. Shaw, March 2001
- Vitamins and Health Supplement Guide: Tryptophan
- Nutritional Supplements Health Guide: The Effects of Tryptophan on Your Body
- National Eosinophilia-Myalgia Syndrome Network: Eosinophilia-Myalgia Syndrome
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