DHEA, or dehydroepiandrosterone, is a steroid hormone that is made from cholesterol and secreted by the adrenal glands, which lie above the kidneys. According to Women to Women, the average adult woman makes 25mg of DHEA per day, although DHEA production declines as a woman ages. Certain conditions, such as adrenal insufficiency, anorexia, kidney disease and depression, may also decrease DHEA production.
DHEA Supplementation
DHEA supplements have been successfully used to increase levels of DHEA in women with adrenal insufficiency and depression. Adrenal sufficiency is a condition in which the adrenal glands do not secrete adequate amounts of hormones. This can lead to fatigue, muscle weakness, loss of appetite, weight loss and irritability. DHEA supplementation can help increase the levels of DHEA in the body and improve mood, sex drive and overall quality of life. DHEA may also help improve mood in women with depression.
Dosage
DHEA is available as a capsule, tablet, injection or topical cream. Dosage for a capsule or tablet usually ranges from 25 to 200mg per day, although the proper dosage for DHEA supplementation for women depends on the form of supplement. The safety and effectiveness of topical creams and intravenous DHEA have not been thoroughly studied, so proper dosage recommendations cannot be made.
Side Effects
The most common side effects of DHEA supplementation in women are headache, insomnia, emotional changes and abnormal menstruation. Because DHEA acts as a precursor to sex hormones, DHEA supplementation may also cause hormonal-related side effects. Women may experience facial hair, hair loss, greasy skin, development of acne, increased sweating and a deepening of the voice. General side effects may include fatigue, nasal congestion, headache or irregular heart rhythms.
Precautions
The use of DHEA supplements may increase blood sugar levels and insulin resistance. Because of this, women with diabetes should not take DHEA supplements. DHEA supplementation should also be avoided during pregnancy or breastfeeding because the hormones may be harmful to the baby. Because DHEA converts to estrogen in the body, women with estrogen-sensitive cancers, such as ovarian and breast cancer, should not take DHEA.
Warnings
The Food and Drug Administration does not regulate the production of DHEA supplements. Because of this, you should use DHEA supplements with caution. Always consult your doctor before beginning any type of supplementation.
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