According to the Agency for Healthcare Research and Quality, 10 to 15 million Americans suffer from depression each year. Symptoms of depression can last for months or even years if not treated. There are numerous prescription medications that are now used for depression, as well as many herbs and vitamins that may be beneficial.
St. John's Wort
According to the National Center for Complementary and Alternative Medicine, St. John's wort, while not effective in relieving major depression, has been found to be effective in cases of minor depression. St. John's wort is available in capsule, tea and extract form. It can interfere with prescription medications so a doctor should always be consulted before use.
SAM-e
SAM-e (S-Adenosyl-L-Methionine) is a compound produced in the human body. Supplementation of SAM-e is thought to help depression. When reviewing clinical studies, the Agency for Healthcare Research and Quality found SAM-e to be more effective than a placebo in improving symptoms of depression. Like St. John's wort, SAM-e can interfere with medications.
Kava
Kava may be helpful for people suffering from depression, as it has been shown to be beneficial in relieving anxiety, a common symptom of depression. There has, however, been some controversy as to the effects of kava on the liver. A doctor should always be consulted before using this herb.
Vitamin B Complex
B vitamins are needed for the brain to function normally. According to Michael Lesser, M.D., deficiencies of some B vitamins, such as folic acid, have been linked to low serotonin levels. Low levels of this neurotransmitter are common in those suffering from depression. Niacin and vitamin B6 are also necessary for serotonin production. Vitamins B12, B1 and B5, while not directly linked to serotonin production, may help with some of the symptoms of depression such as anxiety and fatigue.
Vitamin C
Levels of vitamin C are frequently lower in depressed people than in those who are not. Since no vitamin C is made in the body, it is important to get vitamin C through food and supplements.
Magnesium
In his book, "The Brain Chemistry Diet," Dr. Lesser also recommends magnesium for people suffering from depression, as a deficiency can cause symptoms.
Zinc
Zinc has also been found to be deficient in those suffering from depression. According to the Depression and Bipolar Support Alliance, zinc, along with vitamin C and folic acid, can assist in stabilizing the mood.
References
- National Center for Alternative and Complementary Medicine: St. John's Wort and Depression
- Agency for Healthcare Research and Quality: SAM-e information
- "The Brain Chemistry Diet"; Michael Lesser, M.D.; 2002



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