Protopic is a topical medication that works to decrease the cell activity in the body's immune system. Drugs.com explains that it is often used to slow the growth of atopic dermatitis (eczema) on the skin. The medication comes in an ointment formula containing tacrolimus, an antibiotic that suppresses the immune system, as indicated by RxList.com. As with any medication, Protopic has the risk of side effects.
Less Serious Side Effects
Drugs.com points out that most users of Protopic experience few, if any side effects but the negative response is most often mild. Common side effects include burning, tingling or soreness at the site of application. Early sensitivity is common but diminishes as the tissue becomes accustomed to the medication. Drugs.com points out other side effects including swollen hair follicles, acne, upset stomach, muscle pain, headache or an increased sensitivity to hot or cold temperatures.
Other mild and common side effects, according to RxList.com, may be constipation and cramps.
Serious Side Effects
Individuals who experience more serious side effects should stop using Protopic and contact their doctor. These side effects may include a decline in skin condition or worsening of symptoms, swollen glands or fever with chills, body aches and flu-like symptoms. Drugs.com also identifies a skin infection as a potential side effect. Symptoms include redness, swelling, itching or oozing at the site of application.
RxList.com points out several adverse reactions that are not very common. These include vision abnormalities, abscess of the skin, anemia, anorexia, anxiety, arthritis, bilirubinemia, bone disorder, benign breast masses, bursitis, cataract, chest pain, colitis, ear disorder, joint disorder, gastritis, hernia, laryngitis, lung disorder, migraine, nail disorder, neck pain, oral moniliasis, infection of the outer ear skin, seborrhea, rectal disorder, skin discoloration, skin ulcer, tendon disorder, abnormal thoughts, tooth caries, sweating, vaginal infection and vertigo.
Allergic Reaction
Protpic may not be well-tolerated by some individuals. The reaction can be a sign of allergy. Serious symptoms of an allergic reaction include hives, rash, swelling of the face, swelling of the lips, swelling of the tongue and swelling of the throat. Individuals may have trouble breathing and end up in anaphylactic shock. Emergency medical care is necessary in this situation.



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