A rash and hives from taking a nettle supplement is a sign of an allergic reaction. Although rare, allergic reactions to nettle have been reported, according to Drugs.com. An allergic reaction is a serious medical condition that needs to be reported to your doctor and diagnosed. An allergic reaction can lead to anaphylaxis, a serious reaction that could cause life-threatening symptoms. Rashes are commonly treated with over-the-counter medications but could cause serious complications if the rash develops in the throat or ears.
Allergy to Nettle
An allergy to nettle will cause inflammatory chemicals to be produced in the body that will cause common allergy symptoms. Your immune system reacts to the nettle as if it were dangerous. The body defends itself by creating immunoglobulin E, histamine and other chemicals to fight off the substance. These chemicals cause soft tissue throughout the body to become inflamed. Histamine produced in the upper layer of the skin can trigger various types of skin rashes, including hives. Skin rashes are commonly one of the first symptoms of an allergic reaction.
Hives
Hives can form anywhere on the body within minutes after ingesting nettle. Your skin will become itchy and develop red, raised welts that will cause severe itching and inflammation. Hives form in various shapes and sizes but always have defined borders. The clusters can migrate from one area of the body to another for no apparent reason in a matter of minutes. If you scratch hives, they will become more inflamed and spread faster throughout the body. Hives that form along with swelling in the face and shortness of breath are a sign of anaphylaxis.
Eczema
Eczema is another common rash that can form as a result of an allergic reaction to nettle. Eczema is a pre-existing condition that causes small blisters to form on your body. The blisters typically form on the face, arms and legs and can weep, crust over and leave the skin thick and leathery. Eczema is incurable and can be triggered by various elements, such the weather, clothing or irritants, such as detergents. Eczema is a sign of an allergic reaction.
Treatment
Stop taking nettle supplements if you develop hives or any other rash. You can treat the rashes by taking an oral antihistamine to reduce the amount of histamine your body is creating. You can also apply a steroid-based cream or lotion, such as hydrocortisone to reduce the inflammation and itching.


