Glucosamine is a substance that is naturally found in the cartilage and fluid of your joints. As a supplement, it is bottled as glucosamine sulfate and is made from the shell of certain shellfish or artificially in a lab. It is mostly used to help treat the symptoms associated with arthritis in joints. If you have arthritis, you may consider taking glucosamine for relief.
Glucosamine and Osteoarthritis
Arthritis is a debilitating condition in which your joints begin to degenerate and break down. It can lead to bone-on-bone contact that can be painful with every movement. A meta-analysis conducted by the Cochrane Institute provides proof that glucosamine may be beneficial for arthritic sufferers. This analysis looked at data of studies comparing glucosamine to a placebo and its effects on pain and functionality. The analysis shows that glucosamine can provide a therapeutic effect for people with arthritis. It is a safe supplement that can reduce pain and improve joint function.
Mechanism of Action
Glucosamine can work in one of two ways. Since it is already naturally produced by your body as a component to joints, it can increase the fluid and cartilage that helps support your joints. It may also act to prevent the breakdown of existing cartilage and synovial fluid.
Types of Glucosamine
The types of glucosamine include glucosamine sulfate, hydrochloride and N-acetyl-glucosamine. According to MedlinePlus, glucosamine sulfate is the most tested for joint health and may also be the most effective. Sulfate is a necessary part of cartilage production, so glucosamine sulfate may be more beneficial in joint protection than other forms of glucosamine.
Dosage and Safety
Before taking any new supplement, always consult with your doctor to determine if it is safe for you. Certain supplements have the potential to interact negatively with other medications that you may be taking, so it is important to get clearance from your doctor first. A glucosamine sulfate dosage of 500 mg three times per day for 30 to 90 days is the most commonly tested amount for adults over the age of 18. Children under 18 should avoid taking glucosamine.
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